The Autzen Group is located at the Department of Biomedical Sciences at the Faculty of Health and Medical Sciences, University of Copenhagen (UCPH), Copenhagen N, Denmark. Our group is part of the research division Molecular and Translational Pharmacology, hosting an international and interdisciplinary workplace, and offering a vibrant, creative, and innovative research environment.
The Autzen Group is focused on characterizing the activation and modulation of membrane proteins involved in taste to delineate their basic function and their therapeutic and diagnostic potential. In extension, we are developing tools for detergent-free membrane protein purification to conserve native protein-lipid interactions.
We utilize mammalian expression systems for protein expression and production and employs single-particle cryo-electron microscopy (cryo-EM) in combination with biochemical, biophysical and pharmacological methods for structural and functional characterizations. In addition our group has access to state-of-the-art cryo-EM equipment at the Core Facility for Integrated BioImaging on campus.
NEWS
New preprint! We report the structure of human NHE6, revealing a lipid-stabilized cytoplasmic gate and an extended disordered C-terminus led by postdoc Lukas.
Read Lukas’ preprint here →
JOIN
Open positions are advertised online, but we are continuously looking for new members to join our team. So if you have an idea for a project that aligns with our expertise, you are welcome to inquire.